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Questions & Answers

What is ASAT ?ASAT is offering an alternative to animal testing in chemical safety. Chemical risks are assessed based on information about the biological processes in man that are responsible for the health risks under scrutiny. This replaces information that otherwise would have been generated in experimental animals. ASAT aims at delivering improved health protection for man because it starts from human health risks. It makes the use of experimental animals for chemical safety redundant; chemical safety of our food and consumer products. ASAT is equally relevant for public health protection, occupational health protection and specific exposure conditions such as hobbies or DIY.What is ASAT not !ASAT offers no alternative for other applications of animal testing than testing of chemicals for safety reasons. Based on the current state of development of science and technology it is not plausible that animal testing for other applications can be made redundant. However, progress can be made by applying the 3-R’s principles: refinement, reduction and replacement.These other applications include: • Fundamental and exploratory science, • Research and development of medicines and certain pesticides e.g. rodenticides, • Quality control of medicines.ASAT does not provide a replacement perspective because animal data that have been generated in R&D will be used in safety assessment, side effects in particular. In medicine the application of ASAT is restriced to non mechansim of action related safety issues.Most medicines aim at an effect in people with a disease whereas safety assessment primarily focuses on healthy people.

Questions and Answers about ASAT

Cont.

ASAT

Assurig Safetywithout Animal Testing

ASAT logic is irresistible

ASAT is science based

ASAT is comprehensive

ASAT is global

Benefit to experimental animals

Benefit to environmental protection

Benefit to public health

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